British drugmaker AstraZeneca (AZN.L) said on Thursday it would stop developing its drug brazikumab to treat inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis.
Tag Archive for: ulcerative colitis
Merck will acquire immune-focused Prometheus Biosciences for approximately $10.8 billion, scoring five clinical and pre-clinical candidates for inflammatory bowel and immune-mediated diseases.
In a double data drop yesterday, AbbVie touted two clinical trial wins. Topline data from the Phase III INSPIRE study showed Skyrizi (risankizumab) met its primary and all secondary endpoints in ulcerative colitis and Rinvoq (upadacitinib) aced its Phase II SLEek trial, showing therapeutic potential in systemic lupus erythematosus.
Following a banner year marked by the approval and launch of its diabetes drug Mounjaro, Eli Lilly revealed at the 41st J.P. Morgan Healthcare Conference that it was preparing for another big year.
Findings from Prometheus Biosciences’ Phase II ARTEMIS-UC and Phase IIa APOLLO-CD trials show that PRA023, an anti-TL1A monoclonal antibody, is potentially safe and effective in ulcerative colitis and Crohn’s disease.
Under the terms, biotech firm Roivant will be responsible for funding the development and will retain commercialization rights for RVT-3101, once approved, in the United States and Japan.
Johnson & Johnson’s Janssen unit has sued Amgen Inc. over its plan to market a drug for ulcerative colitis and other conditions similar to J&J’s Stelara, saying it would infringe two patents in a lawsuit made public on Wednesday.
Surrozen announced it paused its Phase I study Crohn’s disease and ulcerative colitis as several healthy participants showed increased levels of liver enzymes.
AbbVie may have doubled in size since the Allergan acquisition, but nearly half the company’s revenue, and a large chunk of its potential future growth, are still coming from a familiar place.