The pharmaceutical industry is finally embracing the idea of engaging with key digital opinion leaders (DOLs) to aid in disseminating information, raising awareness, and educating healthcare professional (HCP) peers in their field. Many articles and case studies have been written about identifying DOLs, mapping their influence, and matching the right DOL to the right campaign. In the past year, an increasingly larger number of medical and commercial teams at pharmaceutical companies have begun to execute these campaigns. The question many companies are now asking is: How do we measure the effectiveness of these DOL efforts?